{
  "name": "ClinicalIntelPulse",
  "description": "The medical intelligence layer for AI agents. Consumer lane: plain-language drug info, drug-drug interaction screening, and recall checks from FDA-approved labels (drug-check, interaction-check, recall-check). Institutional lane: pharmaceutical pipeline and clinical-trial intelligence from 400,000+ ClinicalTrials.gov studies, FDA OpenFDA, and PubMed. 13 endpoints, from $0.10. Pay-per-query via x402 micropayments on Base.",
  "url": "https://clinicalintelpulse.theaslangroupllc.com",
  "version": "1.0.0",
  "capabilities": [
    "fda-label-lookup",
    "patient-medication-safety",
    "drug-recall-check",
    "drug-interaction-screening",
    "medication-info",
    "clinical-trial-intelligence",
    "pharmaceutical-pipeline-analysis",
    "fda-approval-probability",
    "ema-approval-tracking",
    "pdufa-calendar",
    "sponsor-competitive-intelligence",
    "disease-landscape-analysis",
    "drug-mechanism-mapping",
    "global-trial-coverage",
    "who-ictrp-registries",
    "trial-failure-analysis",
    "patient-trial-finder",
    "biotech-ma-signals",
    "licensing-intelligence",
    "pubmed-synthesis",
    "oncology-pipeline",
    "rare-disease-pipeline",
    "neurology-pipeline",
    "cardiovascular-pipeline"
  ],
  "data_sources": [
    "ClinicalTrials.gov REST API v2 — 400,000+ trials (free, no key)",
    "FDA OpenFDA API — NDA/BLA approvals, adverse events (free, no key)",
    "PubMed NCBI E-utilities — 35M+ papers (free, optional key)",
    "WHO ICTRP registries — ChiCTR, CTRI, UMIN, REBEC, ANZCTR, KCT, DRKS + 10 more (via synthesis)",
    "EMA EPAR — European Public Assessment Reports (via synthesis)",
    "PDUFA calendar — FDA action dates (via synthesis)",
    "BioPharma M&A deal data (via synthesis)",
    "FDA OpenFDA drug label (SPL) & enforcement/recall database — plain-language patient medication safety (free, no key)"
  ],
  "coverage": {
    "trials": "400,000+ ClinicalTrials.gov; 200,000+ additional via WHO ICTRP",
    "diseases": "All — oncology, neurology, cardiology, rare diseases, infectious diseases, metabolic, immunology",
    "countries": "190+",
    "languages": [
      "en",
      "es",
      "fr",
      "de",
      "ja",
      "zh",
      "ko",
      "pt",
      "ar",
      "hi"
    ],
    "regulatory_agencies": [
      "FDA",
      "EMA",
      "PMDA (Japan)",
      "NMPA (China)",
      "CDSCO (India)",
      "TGA (Australia)",
      "ANVISA (Brazil)",
      "WHO Prequalification"
    ]
  },
  "payment": {
    "protocol": "x402",
    "network": "eip155:8453",
    "asset": "USDC",
    "contract": "0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913",
    "payTo": "0x50ab2018c06c6E4eAA9BA52057Eb55eD284912fc"
  },
  "endpoints": [
    {
      "path": "/api/clinical/pipeline-scan",
      "method": "GET",
      "description": "Phase 2/3 trial count, sponsor landscape, geographic distribution, mechanism breakdown for any disease.",
      "parameters": [
        {
          "name": "condition"
        },
        {
          "name": "phase",
          "options": "phase2|phase3|both"
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.15,
      "payment_required": true
    },
    {
      "path": "/api/clinical/approval-outlook",
      "method": "GET",
      "description": "FDA/EMA approval probability — PDUFA calendar, success rates, regulatory designations.",
      "parameters": [
        {
          "name": "condition"
        },
        {
          "name": "horizon",
          "options": "12m|18m|24m"
        },
        {
          "name": "agency",
          "options": "FDA|EMA|both"
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.25,
      "payment_required": true
    },
    {
      "path": "/api/clinical/sponsor-intel",
      "method": "GET",
      "description": "Full pipeline by phase, FDA approvals, Phase 3 assets, partnerships for any pharma/biotech company.",
      "parameters": [
        {
          "name": "sponsor"
        },
        {
          "name": "focus",
          "options": "pipeline|approvals|deals|all"
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.2,
      "payment_required": true
    },
    {
      "path": "/api/clinical/disease-landscape",
      "method": "GET",
      "description": "Comprehensive disease brief — approved drugs, mechanism gaps, pipeline map, PDUFA, deals, opportunity score 0-100. Replaces Evaluate Pharma.",
      "parameters": [
        {
          "name": "condition"
        },
        {
          "name": "depth",
          "options": "standard|deep"
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.35,
      "payment_required": true
    },
    {
      "path": "/api/clinical/disease-landscape-lite",
      "method": "GET",
      "description": "$0.25 deterministic preview of disease-landscape — Phase 2/3 trial counts, sponsor rollup, status breakdown, sample trials, no LLM. Upsell to the full report.",
      "parameters": [
        {
          "name": "condition"
        }
      ],
      "price_usd": 0.25,
      "payment_required": true
    },
    {
      "path": "/api/clinical/trial-brief",
      "method": "GET",
      "description": "Full design, endpoints, eligibility, enrollment, outcome for any trial by NCT ID.",
      "parameters": [
        {
          "name": "nct_id",
          "required": true
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.1,
      "payment_required": true
    },
    {
      "path": "/api/clinical/mechanism-map",
      "method": "GET",
      "description": "Approved MOAs, pipeline targets, first-in-class opportunities, white spaces, modality breakdown.",
      "parameters": [
        {
          "name": "condition"
        },
        {
          "name": "mechanism",
          "required": false
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.2,
      "payment_required": true
    },
    {
      "path": "/api/clinical/global-trials",
      "method": "GET",
      "description": "WHO ICTRP registry coverage — ChiCTR, CTRI, UMIN, REBEC, ANZCTR, KCT + regional regulatory landscape.",
      "parameters": [
        {
          "name": "condition"
        },
        {
          "name": "region",
          "options": "global|africa|asia|europe|latin-america|middle-east|north-america"
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.15,
      "payment_required": true
    },
    {
      "path": "/api/clinical/failure-analysis",
      "method": "GET",
      "description": "Phase 2→3 and Phase 3→approval success rates, failure taxonomy, named failed trials, lessons for new programs.",
      "parameters": [
        {
          "name": "condition"
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.2,
      "payment_required": true
    },
    {
      "path": "/api/clinical/patient-finder",
      "method": "GET",
      "description": "Plain-language recruiting trial finder for patients — accessible eligibility, application guide, advocacy resources.",
      "parameters": [
        {
          "name": "condition"
        },
        {
          "name": "country",
          "required": false
        },
        {
          "name": "phase",
          "options": "phase2|phase3|any"
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.1,
      "payment_required": true
    },
    {
      "path": "/api/clinical/deal-signal",
      "method": "GET",
      "description": "Biotech M&A signals — acquisition targets with deal values, recent comps, likely acquirers, timing signals.",
      "parameters": [
        {
          "name": "condition"
        },
        {
          "name": "deal_type",
          "options": "acquisition|licensing|both"
        },
        {
          "name": "stage",
          "options": "phase2|phase3|both"
        },
        {
          "name": "lang"
        }
      ],
      "price_usd": 0.35,
      "payment_required": true
    },
    {
      "path": "/api/clinical/deal-signal-lite",
      "method": "GET",
      "description": "$0.25 deterministic preview of deal-signal — Phase 2/3 trial counts, industry-sponsored candidate-asset list, no LLM. Upsell to the full report.",
      "parameters": [
        {
          "name": "condition"
        },
        {
          "name": "stage",
          "options": "phase2|phase3|both"
        }
      ],
      "price_usd": 0.25,
      "payment_required": true
    },
    {
      "path": "/api/clinical/trial-check",
      "method": "GET",
      "description": "ClinicalTrials.gov lookup — single trial by NCT id or filtered search, deterministic — Trial status, phase, sponsor, enrollment, dates and countries by NCT id, or search by condition/sponsor with phase and status filters. Typed records straight off the official v2 API. No LLM, public domain.",
      "parameters": [
        {
          "name": "nct",
          "required": false,
          "description": "Single trial by NCT id, e.g. NCT02142738"
        },
        {
          "name": "condition",
          "required": false,
          "description": "Search by condition"
        },
        {
          "name": "sponsor",
          "required": false,
          "description": "Search by sponsor"
        },
        {
          "name": "phase",
          "required": false,
          "description": "1|2|3|4"
        },
        {
          "name": "status",
          "required": false,
          "description": "RECRUITING | COMPLETED | ..."
        },
        {
          "name": "limit",
          "required": false,
          "description": "1-25, default 10"
        }
      ],
      "price_usd": 0.02,
      "payment_required": true
    },
    {
      "path": "/api/clinical/drug-check",
      "method": "GET",
      "description": "What is this medication? (plain language) — Plain-language explainer for any prescription or OTC drug from its FDA-approved label — what it treats, how to take it, boxed warnings, who should not take it, common and serious side effects, pregnancy notes. Data: FDA openFDA drug label.",
      "parameters": [
        {
          "name": "drug",
          "required": true,
          "description": "Brand or generic medication name — e.g. 'Ozempic' | 'metformin' | 'ibuprofen'"
        }
      ],
      "price_usd": 0.1,
      "payment_required": true
    },
    {
      "path": "/api/clinical/interaction-check",
      "method": "GET",
      "description": "Can these medications be taken together? — Cross-references the FDA-approved drug-interaction and contraindication sections for 2+ drugs and flags possible interactions in plain language, with severity and what-to-do. Data: FDA openFDA drug label.",
      "parameters": [
        {
          "name": "drugs",
          "required": true,
          "description": "Two to eight medication names, comma-separated — e.g. 'warfarin,ibuprofen'"
        }
      ],
      "price_usd": 0.15,
      "payment_required": true
    },
    {
      "path": "/api/clinical/recall-check",
      "method": "GET",
      "description": "Is my medication recalled? — Checks the FDA enforcement database for active and past recalls of a drug, explains the recall class (I/II/III) in plain language, and lays out what to do. Data: FDA openFDA enforcement.",
      "parameters": [
        {
          "name": "drug",
          "required": true,
          "description": "Brand or generic medication name — e.g. 'metformin' | 'valsartan'"
        }
      ],
      "price_usd": 0.1,
      "payment_required": true
    }
  ],
  "openapi": "https://clinicalintelpulse.theaslangroupllc.com/openapi.json",
  "llms_txt": "https://clinicalintelpulse.theaslangroupllc.com/llms.txt",
  "contact": "info@theaslangroupllc.com",
  "operator": "The Aslan Group LLC"
}
